KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRMT3
All Species:
22.73
Human Site:
S414
Identified Species:
41.67
UniProt:
O60678
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60678
NP_005779.1
531
59903
S414
L
D
P
K
T
L
I
S
E
P
C
G
I
K
H
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001092890
531
59784
S414
L
D
P
K
T
L
I
S
E
P
C
G
I
K
H
Dog
Lupus familis
XP_534089
541
60618
S424
L
D
P
K
T
L
I
S
D
A
C
S
I
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q922H1
532
59884
D415
T
L
I
S
D
P
C
D
I
K
M
D
G
K
H
Rat
Rattus norvegicus
O70467
528
59401
S411
V
D
H
K
T
L
I
S
D
P
C
D
I
K
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505718
571
63850
S454
L
D
P
K
T
L
I
S
E
S
C
V
I
K
R
Chicken
Gallus gallus
XP_420907
526
59430
S409
L
D
P
S
T
L
I
S
E
A
S
I
I
K
H
Frog
Xenopus laevis
Q8AV13
369
42306
V253
N
A
C
L
I
K
E
V
D
I
Y
T
V
K
V
Zebra Danio
Brachydanio rerio
Q5RGQ2
419
48204
V303
N
S
C
L
V
K
E
V
D
I
Y
T
V
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396035
525
60169
L408
E
I
C
N
S
E
E
L
I
T
S
I
V
E
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192186
519
58632
T402
V
D
P
D
T
V
M
T
K
P
C
M
I
K
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O82210
366
41153
M250
D
S
K
L
L
K
T
M
D
I
S
K
M
A
A
Baker's Yeast
Sacchar. cerevisiae
P38074
348
39768
I232
F
D
L
N
T
V
K
I
S
D
L
A
F
K
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.1
90.9
N.A.
89.8
89.2
N.A.
78.8
70.8
35.4
35.7
N.A.
N.A.
42.5
N.A.
45
Protein Similarity:
100
N.A.
96.8
95.1
N.A.
93.9
93.9
N.A.
85.9
83.2
49.1
52.3
N.A.
N.A.
62.5
N.A.
63.6
P-Site Identity:
100
N.A.
100
73.3
N.A.
13.3
73.3
N.A.
80
73.3
6.6
6.6
N.A.
N.A.
0
N.A.
46.6
P-Site Similarity:
100
N.A.
100
80
N.A.
13.3
86.6
N.A.
80
73.3
20
20
N.A.
N.A.
20
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.1
31.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.2
43.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
0
16
0
8
0
8
8
% A
% Cys:
0
0
24
0
0
0
8
0
0
0
47
0
0
0
8
% C
% Asp:
8
62
0
8
8
0
0
8
39
8
0
16
0
0
0
% D
% Glu:
8
0
0
0
0
8
24
0
31
0
0
0
0
8
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
16
8
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
39
% H
% Ile:
0
8
8
0
8
0
47
8
16
24
0
16
54
0
8
% I
% Lys:
0
0
8
39
0
24
8
0
8
8
0
8
0
85
0
% K
% Leu:
39
8
8
24
8
47
0
8
0
0
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
8
8
0
0
8
8
8
0
0
% M
% Asn:
16
0
0
16
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
47
0
0
8
0
0
0
31
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
0
16
0
16
8
0
0
47
8
8
24
8
0
0
8
% S
% Thr:
8
0
0
0
62
0
8
8
0
8
0
16
0
0
8
% T
% Val:
16
0
0
0
8
16
0
16
0
0
0
8
24
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
16
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _